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Friday, October 3, 2014

Stratech Scientific's Molecular Cell Biology Products

Stratech Scientific supply Molecular Biology products from a range of different manufacturers, to give you all the reagents you need for your experiments in one place.  Additional information on this range can be found on the following pages:

Product Focus: His-STREPPER Kit

IBA's new His-STREPPER- the His/Strep-tag®II Adapter - is a molecule comprising Strep-tag®II (SA-WSHPQFEK) conjugated with a nickel charged trisNTA. It tightly binds to 6xHis-tag and thereby converts a 6xHis-tag fusion protein to a Strep-tag®II fusion protein without the need for cloning.

The His-STREPPER Trial Kit (2-0920-999) provides all reagents for 3 applications.
  • His-STREPPER adapter
  • Strep-Tactin Superflow column
  • Wash buffer
  • Elution buffer
  • Regeneration buffer
More information (pdf 1.1MB)

For additional information contact info@stratech.co.uk.

Product Focus: Anti-mouse CD31 / DIA-310 Rat monoclonal anti-mouse endothelial cell marker CD31 (PECAM-1), Clone SZ31

Antibody clone SZ31 is the first antibody which reacts specifically with murine CD31 in formalin-fixed paraffin-embedded tissue sections.

CD31, also known as PECAM-1 (Platelet Endothelial Cell Adhesion Molecule-1) is expressed constitutively on the surface of embryonic and adult endothelial cells. It is also expressed on cell surfaces of monocytes, neutrophils, platelets and certain T-cell

subsets. It has been detected on bone marrow-derived hematopoetic stem cells and embryonic stem cells. CD31 is a 130kDa integral membrane glycoprotein and as a member of the immunoglobulin superfamily involved in the mediation of cell-to-cell adhesion.

CD31-mediated endothelial cell-cell interactions play a major role in angiogenesis. Studies have shown CD31 to be a superior marker in human angiogenesis, which reportedly predicts tumor recurrence. Pathophysiological studies of CD31 in murine model systems had limitations because standard formalin-fixed sections were excluded. The clone SZ31 eliminates these restrictions by allowing high quality immunohistochemical analysis of standard formalin-fixed paraffin sections in mice.


Product Information

MSDS        Datasheet

 

Catalogue numbers: DIA-310 (100μg)
DIA-310-M (20μg)
Specificity: CD31
Species Reactivity: Mouse
Host Species: Rat
Isotype: IgG2a
Clone: SZ31
Clonality (Mono-/Polyclonal): monoclonal
Application: Immunohistochemistry (IHC), Paraffin Sections (PS), Frozen Sections (GS), Western Blot
Conjugation: unconjugated
Format: lyophilisate, antibody purified (from culture supernatant)
Intended Use: for Research Use Only
Research Area: angiogenesis, CD markers, immunohistochemistry  


Where can I find more information about Dianova?

Visit the manufacturer page at www.stratech.co.uk/dianova, email info@stratech.co.uk or call +44 (0) 1638 782600.

Stratech Scientific is a distributor of high quality, competitively priced, reliable products for research laboratories throughout the UK and Europe. Please contact us to find out which ranges we can supply in your country.